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Levothyroxine, also L-thyroxine or T4, is a synthetic way of the thyroid hormone thyroxine, which is normally secreted by thefollicular cells of the thyroid gland. It is also employed to go into thyroid hormone deficiency, and off to abort the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is chemically in the chiral L-form. The correlated sedative dextrothyroxine (D-thyroxine) was habituated to in the ago as a treatment for hypercholesterolemia (exalted cholesterol levels) but was reticent fitting to cardiac side-effects.
Experience
Thyroxine was first secret in unalloyed appearance in 1914 at the Mayo Clinic past Edward Calvin Kendall from extracts of hog thyroid glands.[3 - The hormone was synthesised in 1927 by way of British chemists Charles Robert Harington and George Barger.
Medical uses
Levothyroxine is typically hand-me-down to treat hypothyroidism.[4 - It may also be old to treat goiter via its faculty to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.[5 - [6 - In 1992, President George H.W. Bush told telly pack Larry Prince that he had been prescribed levothyroxine as corner of a treatment regimen as a service to Graves' contagion; the exchange was relay contemporary to satellite dish owners tracking and recording backhaul channels.[7 -
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